Near Isogenic Lines

[jcm05]

This term came out of a paper at the link below that Mark posted. Can one of you guys dumb this down a bit and explain it? Thanks.

tgc.ifas.ufl.edu/2007/2007IndividualAbsPDf/Merk.pdf

[frogsleapfarm]

Isogenic lines are used to compare the effect of a single gene/allele, in lines that are "identical" in all other respects. This isolates the effect of a particular gene/allele, without confounding background germplasm effects. True isogenic lines are hard to produce, so near isogenic lines are often used for these comparisons. As Keith points out even this usually takes several generations of backcrossing.

[jcm05]

OK, makes more sense now. Thanks.